The simplest one is to wager on the in-form golfers, a list led by Rory McIlroy and Scottie Scheffler. McIlroy may get the nod over Scheffler in some circles this week because he's playing on home soil at Royal Portrush in Northern Ireland.

It’s going to be a big sports weekend, as the Open Championship continues, plus UFC 318 and Pacquiao vs. Barrios are headlining events on Saturday. With our exclusive BetMGM bonus code MLIVE, you can wager just $10 on any market and snare $150 in bonus bets if the initial bet is graded as a winner.

SportsLine golf expert Eric Cohen locked in a $10 eight-leg PGA Tour parlay that would return nearly $1.1 million for the British Open 2025

Here are The Open betting odds for a top five finish. The Open 2025 odds on the top five are lower than the outright winner odds as golfers have a higher probability of finishing in the top five. This can provide potential value for bettors looking to back outsiders without the player having to win the event.

Russell Henley has +6500 odds to win the 2025 Open Championship at Royal Portrush Golf Club as he tries to follow up his fifth-place showing at this tournament in 2024 with another high finish. Henley has one win, and an average finish of 16th, in his 19 events during the past year (including six top fives).

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Get the latest odds for Sepp Straka to win The Open Championship at Royal Portrush Golf Club, July 17-20, plus props and other betting options.

But nobody should ever mistake artificial intelligence for being sappy. USA TODAY Sports canvassed five major AI programs seeking their predictions for the 2025 Open Championship winner and top sleeper picks. The majority went with the pre-tournament favorite, Scottie Scheffler, who is seeking his first Claret Jug.

Robert MacIntyre, who placed sixth in the 2019 The Open Championship at Royal Portrush Golf Club, comes into the 2025 Open Championship with +3500 odds to win as he tries for another strong performance. In the past 12 months, MacIntyre has played in 23 tournaments. His best finish was second, and his average finish was 27th, with one top five.

There is a five-way tie for the lead after the first round of the 153rd Open Championship with Jacob Skov Olesen, Haotong Li, Matt Fitzpatrick, Christiaan Bezuidenhout and Harris English shooting 4-under 67 Thursday at Royal Portrush. World No. 1 Scottie Scheffler (68) is one back with home favorite Rory McIlroy (70) three off the pace.