Casas was removed in the bottom of the second inning after suffering what manager Alex Cora described as a “significant (left) knee injury.”

Casas suffered the injury when he hit first base awkwardly trying to beat out an infield single in the second inning. He hit the bag and immediately crumbled to the ground, grabbing his left knee. Casas had to be carted off the field. Here's the play:

The 25-year-old suffered the injury running to first on a slow roller in Boston's win over the Twins on Friday night.