For decades, opioids have been the blunt instrument of modern pain care, powerful enough to quiet severe suffering yet risky ...

New research reveals previously unknown ways opioid receptors can function, opening the door to safer pain treatments.

Julie Blendy, professor of pharmacology at University of Pennsylvania’s Perelman School of Medicine, presented her research on the molecular and genetic mechanisms behind opioid use disorders in the ...

Co-occurring disorders and clinical care for complex illnesses- safe and effective use of opioids may be only one of the ...

Experiments reveal that a time-dependent epistatic interaction influences how mice respond to opioids, and that intracellular fibroblast growth factors also influence opioid sensitivity.

New medications are in the pipeline that could help people win their battles against addictive substances, including opioids ...

Opioids are a class of medication that doctors may prescribe to treat severe or persistent pain. However, opioids that people may use illegally, such as heroin, also exist. However, people do not ...

Opioids are powerful painkillers. Benzodiazepines (benzos) are strong sedatives that are prescribed for anxiety or sleep problems. Each of these medicines has side effects. Both drugs can be addictive ...

Despite irrefutable pharmacological evidence of the wide range in individuals' metabolism of opioid drugs, states continue to impose "one-size-fits-none" laws. For example, Massachusetts, apparently ...

Chronic pain is one of the most common and expensive health problems in the nation, affecting an estimated one in five U.S. adults and costing around $600 billion each year in medical expenses, lost ...

Long before opioids flooded communities, something else was quietly changing—and it may have helped set the stage for today’s crisis. A new study finds that as church attendance dropped among ...