The glymphatic system was first explained 1 as a macroscopic waste clearance system that utilizes astroglial (glial-lymphatic) channels to eliminate soluble proteins and metabolites from the central ...

Fighting Alzheimer’s disease is a race against time. By the time most patients are diagnosed and treated, their cognitive symptoms have already advanced significantly. New research, though, pinpoints ...

Cerebrospinal fluid (CSF) circulates through the central nervous system, providing mechanical protection, nutrient delivery and metabolic waste clearance. In recent years, the concept of a glymphatic ...

A multitude of genes have been linked to the development of Alzheimer's disease. Specifically how those genes might influence the progression of neurodegeneration remains something of a black box ...

Research headed by teams at the University of Rochester Center for Translational Medicine and the University of Copenhagen describes for the first time how a spreading wave of disruption and the flow ...

Brain-derived extracellular vesicle (EV) biomarkers represent a promising frontier for liquid biopsy development targeting the nervous system. They offer strong potential for enabling minimally ...