Definition: DNA amplification is the laboratory process of making many copies of a selected DNA sequence from a very small starting amount. It allows DNA that would otherwise be too scarce to detect ...

A team of researchers from the Case Western Reserve University School of Medicine has developed a new method for target DNA sequence amplification, testing and analysis. This new technique, or ...

Quantitative polymerase chain reaction (qPCR) is a molecular technique that has reshaped the landscape of biological research and medicine due to its high sensitivity and specificity. qPCR, also known ...

Despite its utility, PCR’s main limitation is that it requires precise cycles of heating and cooling to amplify DNA. The thermal cyclers that perform this operation are clunky, relatively expensive, ...

New study finds two next-generation whole-genome sequencing systems deliver broadly similar accuracy in detecting genetic variants. Read more.

With just a room-temperature “pot,” a sprinkling of molecules, and a simple electrical device, pathogen DNA detection can now be achieved in under an hour anywhere. This method creates ...

PCR genetic analysis has been in the spotlight since COVID-19, but light is now further facilitating PCR-free methods. Osaka Metropolitan University scientists have developed a light-induced DNA ...

Real-World Plasma Thymidine Kinase Activity in High-Risk and Metastatic Hormone Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative Breast Cancer Treated With Cyclin-Dependent Kinase ...

A label-free nanopore platform uses programmable DNA circuits to build versatile molecular logic gates, forming a universal basis for scalable DNA computing and advanced biosensing applications.