Genes are segments of DNA (deoxyribonucleic acid) that are located inside every human cell. The DNA inside each cell is tightly coiled in structures called chromosomes. Each chromosome contains a ...
A new article analyzes in depth the physical problems associated with DNA packaging that have often been neglected in structural models of chromosomes. The study demonstrates that the multilaminar ...
One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published in Nature. Chromosomes are thread-like structures that carry a cell's ...
Pt. A. Gene cloning -- cDNA cloning method using stable expression in mammalian cells / Toru Miki and Stuart A. Aaronson -- Normalization and selection with short-fragment cDNAs / Satish Parimoo, ...
Researchers have unveiled a way to flip genes back on without slicing into the genome, a shift that could make CRISPR far ...
Humans have 23 pairs of chromosomes, including a pair of sex chromosomes (typically XX for females, and XY for males). Chromosomes contain hundreds to thousands of genes, which are sections of DNA ...
Small, cancer-associated DNA circles "hitchhike" on chromosomes during cell division to spread efficiently to daughter cells by co-opting a process used to maintain cellular identity through ...
Researchers at The Institute of Cancer Research, London identified the CIP2A–TOPBP1 complex as a master regulator of DNA repair during mitosis, coordinating backup pathways that protect chromosomes ...