MAPK signaling works like a molecular switchboard inside epithelial cells, turning outside stress into gene-level commands. IL-33 is an alarm signal cytokine that normally stays tucked inside ...

Idiopathic pulmonary fibrosis (IPF) is a chronic disease in which healthy lung tissue is gradually replaced by scar tissue.

Chinese scientists have discovered a common mechanism by which structurally distinct proteins elicit an allergic reaction, showing they cause the formation of pores in epithelial airway cells. That ...

In 2020, right when Jane Baude was starting her Ph.D. research at UC Santa Barbara, she learned that a critical component of her experiment — the gel needed to grow and test mammary epithelial cells — ...

The mucosal immune system is comprised of anatomically remote and physiologically independent compartments that protect ocular, nasopharyngeal, respiratory, oral, gastrointestinal, and genitourinary ...

Study data indicate that membrane perforation registers as danger and is sufficient to launch type 2 immune pathways in the airway epithelium. The authors argue that many otherwise unrelated allergens ...