This study systematically elucidates the drug resistance mechanisms of five highly pathogenic viruses, proposes five ...

A new study headed by teams at the Wellcome Sanger Institute, EMBL’s European Bioinformatics Institute (EMBL-EBI), and Open Targets has indicated how mutations that cause cancer drug resistance fall ...

Table 1. Commercial assays available for HBV DNA quantitation. Method Commercial kits Lower limit of detection Ref. If ALT becomes persistently elevated, consider biopsy, especially in individuals ...

Drug resistance remains an important challenge for Warshel, even if HIV itself is too unruly a system to conquer with current tools. But the broader lesson, he said, is that maximum entropy has become ...

All cancer mutations that cause drug resistance fall into one of four categories. New research has detailed each type, helping to uncover targets for drug development and identify potential effective ...

One of the most challenging moments in cancer treatment comes when a therapy stops working. In many metastatic cancers, drugs ...

In a recent study published in the journal Nature Biotechnology, researchers in Switzerland used base and prime editing to create and analyze a wide array of variants of the epithelial growth factor ...