A new study describes a technique that rejuvenates aging blood-forming stem cells and could help reduce the risk of age-related blood disorders.

What Is a Lysosomal Storage Disorder? Lysosomal storage disorders are a group of more than 50 rare diseases. They affect the lysosome — a structure in your cells that breaks down substances such as ...

Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, report in Nature Communications on how the targeted suppression of lysosome function may lead to brain cancer therapy.

The duplication and division of cells is critical to keeping all multicellular organisms alive. But the opposite process is equally important: cell death. Controlled death of cells, or programmed cell ...

Lysosomes are membrane-bound organelles whose acidic lumen (pH 4.5–5.0) is required for degradation. This luminal acidity is known to regulate cytosolic-side functions such as membrane fusion/fission, ...

Imagine a child who keeps falling sick, looks pale, and has a swollen belly. The parents visit many doctors but find no answers. Finally, after months of worry, the child is diagnosed with a lysosomal ...

Macrophages rely on lysosomes to balance microbial killing with self-protection, generating reactive oxygen and nitrogen species during phagocytosis. Using platinum nanoelectrodes, researchers at ...