By Tarun Sai Lomte A large genetic analysis suggests that one amino acid linked to protein metabolism could influence how ...

A new research paper was published in Volume 18 of Aging-US on February 6, 2026, titled "Causal effects of inflammation on long-term mortality: a Mendelian randomization study." ...

A higher body mass index (BMI) appears to be causally related to a greater risk for vascular-related dementia.

Metabolic dysfunction, rather than steatotic liver disease (SLD), seems to be the main driver of chronic kidney disease (CKD) ...

IL6 and IL6R appear to be biologically opposing causal regulators of human survival: IL6 increases, while IL6R reduces mortality through ...

The comparison of publications/citations in Mendelian randomisation from 2015 to 2024. On the top, it reflects the trend of total publications and citations each year. The keywords in this field are ...

Traditional epidemiological studies have identified numerous potential risk factors, but observational studies have struggled to establish causal links due to confounding factors and reverse causation ...

Inflammation is the body’s natural way of healing itself when there’s an injury or infection. It helps protect us and repair damage. But when inflammation lasts too long, it can become harmful instead ...

Introduction to Mendelian randomization, the problems with using traditional observational studies to investigate causality, and Randomized controlled trials as the gold standard for causal research.