Mitochondrial DNA heteroplasmy is independently associated with an increased risk of CLL, suggesting potential as a novel biomarker for early risk identification.

A previously unknown type of DNA damage in the mitochondria, the tiny power plants inside our cells, could shed light on how our bodies sense and respond to stress. The findings of the UC ...

David Rand, a professor of natural history at Brown University, explains how studying mitochondria — the cell's energy producers — offers a useful way to understand complex gene-by-gene or ...

Nucleotide synthesis-the production of the basic components of DNA and RNA-is essential for cell growth and division. In most animal cells, this process depends closely on properly functioning ...

Researchers introduced a yeast enzyme, ScURA, into human cells, enabling nucleotide synthesis independent of mitochondrial ...

Mitochondrial DNA has long been treated as a workhorse record of cellular history, but new research suggests it also hides a subtle and previously overlooked form of damage. By uncovering this cryptic ...

It's long been assumed the Jomon people, who had inhabited the Japanese archipelago since around 16,000 years ago, had multiple lineages resulting from different migration routes. But new genetic ...

New molecule halts mitochondrial DNA loss before it triggers inflammation. When environmental stress harms DNA, it can set off a cascade of failures linked to heart conditions, neurodegeneration and ...

Researchers have discovered a key molecular process that may contribute to chronic inflammation as we age. If this process can be accurately targeted, it could unlock ways to stay healthier in our ...