The sudden passing of Eleanor Carol Barr, the 39-year-old wife of U.S. Rep. Andy Barr of Kentucky, is putting the spotlight on mitral valve prolapse, or floppy valve syndrome, listed as the cause of ...

Mitral valve prolapse (MVP) is a common congenital abnormality of the heart that can cause severe complications such as arrhythmias, heart failure, and sudden cardiac death. To date, the causes of MVP ...

Most cells in the body have a small appendage called a primary cilium. In recent years, a variety of studies have linked the cilium to "the vast majority" of cellular signaling pathways, and cilia ...

A man found dead in the Stark County Jail last spring died from natural causes, the Stark County Coroner’s Office said. His ...

A global research collaborative including Medical University of South Carolina investigators report in today's Science Translational Medicine that defects in the primary cilia of the developing fetus ...

An international research collaboration led by Massachusetts General Hospital (MGH) investigators has identified the first gene in which mutations cause the common form of mitral valve prolapse (MVP), ...

The larger the sail, the more wind it catches. But as that size increases, so does the stress experienced by each sheet and line connected to the canvas. The same thing can be said for a heart with ...

Cells with faulty antennae that can’t get their signals straight may be behind a common heart valve disorder. Newborn mice engineered to develop a flawed heart valve had stunted primary cilia in cells ...

The mitral valve controls the flow of blood from the heart’s left atrium down to the left ventricle, where it is pumped out to the body. When part of the valve doesn’t close properly, it’s called ...

Your heart has four chambers, two on the right and two on the left. Blood flows into the right side of the heart, then to the lungs where it receives oxygen. From the lungs it flows into the left ...

Myxomatous degeneration is the buildup of certain molecules in heart valve tissue, causing the valve to become loose or weak. Severe cases can lead to complications like heart failure. Myxomatous ...

Genetic mutations in heart valve cells of the developing fetus lead to mitral valve prolapse, report a global collaborative of researchers. These mutations or genetic variations cause defects in ...