Click on each game for NFL Week 10 picks, NFL Week 10 predictions, NFL Week 10 win probabilities and NFL Week 10 odds for that game.

Despite the Saints' trend of Unders, the SportsLine Projection Model likes Over 39.5 as that hits in 57% of the model's 10,000 simulations. The Panthers have been great at home and outside of a 9-point showing in a 40-9 loss to Buffalo, Carolina has scored 27, 30 and 30 in its other three home games this season.

Here we will look at and discuss some bold predictions for the game between the Saints and the Rams in Week 9 of the 2025 NFL season.

Jonathan Taylor completed a 244-yard rushing day with an 8-yard touchdown run in overtime to give the Indianapolis Colts a 31-25 victory over the Atlanta Falcons on Sunday in the first

Taylor ran all over the Falcons defense for a career-high 244 yards. The Colts rushed for 323 yards and racked up 519 total yards of offense in Week 10. Despite another impressive performance by wide receiver Drake London (six catches for 104 receiving yards and one touchdown),