AXS-12 reduced the frequency of cataplexy attacks per week compared with placebo (P =.017). Topline results were announced from a phase 3 trial evaluating AXS-12 (reboxetine) in patients with ...

Narcolepsy was linked to high blood pressure, hyperlipidemia, and diabetes on top of outright cardiovascular disease events in a retrospective cohort study. Notably, patients with narcolepsy started ...

People with narcolepsy often need to take medicines to manage their symptoms. Many of these medicines carry a high risk for abuse or misuse, so there are restrictions on how they are prescribed and ...

Narcolepsy is caused by a deficiency of orexin, a brain chemical that regulates wakefulness and REM sleep. The MSLT and polysomnography are gold standards for diagnosing narcolepsy. Medications like ...

SAN DIEGO — The investigational drug AXS-12 (reboxetine, Axsome Therapeutics) is safe and effective for the treatment of cataplexy (emotionally induced muscle weakness) and excessive daytime ...

Narcolepsy affects how you sleep and stay awake. You can feel very sleepy during the day and may suddenly fall asleep without warning. Narcolepsy symptoms can come and go or change over time. Some ...

While no clear link has been established between autism spectrum disorder and narcolepsy, shared neurological pathways may underlie overlapping symptoms and dual diagnosis. Narcolepsy is a ...