The NF-κB-inducing kinase (NIK), a molecule pivotal for immune system development and function, shows significant yet complex potential as a therapeutic target. The comprehensive review, published by ...
Receptor tyrosine kinases (RTKs) regulate many critical biological processes such as cell growth, differentiation, and survival through the recruitment of intracellular signaling molecules. The ...
Two decades ago, Professor Shao-Cong Sun first discovered the non-canonical NF-κB pathway mediated by NF-κB-inducing kinase (NIK). Since then, more ...
Prognostic impact of androgen receptor (AR) and forkhead box A1 (FOXA1) in early HER2-negative primary breast cancer: A translational substudy of the prospective phase III WSG-PlanB-trial. This is an ...
From studies conducted on animals, evidence has emerged that both neutralizing activity and Fc-mediated effector functions of neutralizing antibodies provide some levels of protection against the ...
Like animals, plants need to be on a constant lookout to recognize and respond to invasion by microbes. Plant immunity consists of two branches—the initial defense begins with the detection of ...
Exl-111 is an investigational allergic Effector Cell Response Inhibitor (ECRI) targeting the IgE axis and is designed to disarm allergic ...
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