For the first time ever, scientists are attempting to reverse cellular aging in a living patient. The target: incurable ...

Test time has arrived: the first person has been treated in a highly anticipated gene therapy trial that aims to coax aged ...

Aging, at its most fundamental level, is a molecular process. Chemical marks on the genome shift and lose fidelity over time, ...

Scientists reprogram brain immune cells to fight Alzheimer's: Study ...

Promising mouse studies and billions of dollars in funding are stoking excitement. But we’ve been here before.

A gastrointestinal oncologist told Newsweek that the early-stage findings are a “major step forward” in targeting colon ...

Researchers at Oregon Health & Science University have uncovered a key reason why immunotherapy has largely failed in pancreatic cancer—and identified a promising strategy to overcome that resistance.

Manipulating cell identity through transcription factor-mediated reprogramming, induced pluripotency or directed differentiation holds promise for disease modelling and regenerative medicine. Yet the ...

Leuven, 11 March 2025 – Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center ...

In order to reprogram readily available cells into specific immune cells that fight various diseases, one must know the "recipe" for the transformation. Researchers at Lund University have now created ...

Decoding and reprogramming cells — the fundamental units of life — remains one of the most profound challenges in modern biology. Historically, the identity of a differentiated cell was viewed as ...

A newly identified molecule called OLE helped restore the brain’s immune cells to a more protective state in Alzheimer’s ...