How does a single cell build a brain with billions of precisely organized neurons? Researchers suggest that brain cells use ...
A new study constructs the first 3D single-cell brain atlas of the lamprey, uncovering the 450-million-year-old molecular blueprint of vertebrates.
Single-cell spatial transcriptomes have demonstrated molecular and cellular diversity in the brain, but gene regulatory mechanisms underlying transcriptomic profiles and disease pathogenesis remain ...
Scientists from Duke-NUS Medical School and their collaborators have created one of the most comprehensive single cell maps of the developing human brain. The atlas captures nearly every cell type, ...
This study explores the neurobiological underpinnings of alcohol use disorder (AUD) by integrating bulk and single-cell transcriptomic data from humans, primates, and mice across three brain regions ...
Developing neocortex in Down syndrome. IT neurons are labeled in magenta and deep-layer neurons in green. IT and double-positive neurons are increased in DS at this stage [de la Torre-Ubieta Lab] A ...
Immunology researchers are working to understand complex adaptive immune responses, but meaningful signals are often rare, transient, or difficult to capture across large, sample-limited studies.