Replication protein A (RPA) is a eukaryotic single-stranded DNA–binding protein involved in processes including replication, recombination, transcription, checkpoints, telomere maintenance and DNA ...

Can we stay young forever, or even recapture lost youth? Research from the laboratory of Professor Julian Chen in the School of Molecular Sciences at Arizona State University recently uncovered a ...

Telomeres are stabilized, and telomeric DNA is replenished, by the action of the ribonucleoprotein reverse transcriptase telomerase. Telomere capping functions include the ability of telomeres to ...

Understanding the underlying mechanism of telomerase action offers new avenues toward effective anti-aging therapeutics. illustration depicting the enzyme telomerase This figure depicts the enzyme ...

Research from the laboratory of Professor Julian Chen in the School of Molecular Sciences at Arizona State University recently uncovered a crucial step in the telomerase enzyme catalytic cycle. This ...

Telomeres are specialized nucleoprotein structures at the ends of eukaryotic chromosomes that are essential for chromosome stability and cellular proliferation. Telomeric DNA does not encode for ...

Elizabeth H. Blackburn won the 2009 Nobel Prize in Physiology or Medicine along with Carol Greider and Jack Szostak for discovering “how chromosomes are protected by telomeres and the enzyme ...

A new mechanism that slows down and may even prevent the natural ageing of immune cells – one of the nine ‘hallmarks of ageing’* – has been identified by an international team led by UCL scientists.

A new mechanism that slows down and may even prevent the natural aging of immune cells – one of the nine 'hallmarks of aging' – has been identified by an international team led by UCL scientists.

Science has identified in the plant kingdom the “missing link” of cellular immortality between human and single-celled animals, according to a new study led by scientists from Arizona State University ...

Scientists at the University of Colorado’s BioFrontiers Institute, in an article published in the journal Nature, have identified a new target area within human DNA that may be susceptible to future ...

Research from the laboratory of Professor Julian Chen in the School of Molecular Sciences at Arizona State University recently uncovered a crucial step in the telomerase enzyme catalytic cycle. This ...