Khamenei has condemned the attacks and promised to retaliate, saying Israel had "sealed for itself a bitter and painful destiny."

Israeli Prime Minister Benjamin Netanyahu told ABC News on Monday that targeting Iran's Supreme Leader Ali Khamenei would end, not escalate, the ongoing fight between Israel and Iran that erupted late last week.

Day four of intensifying hostilities between Iran and Israel draws to a close, but with no end to the exchanges of missiles and drones in sight. Euronews has this roundup of the key events from Monday evening.

Iran has already developed a range of options to retaliate for strikes from Israel or the United States, potentially plunging the region into deeper turmoil

Israel launched blistering attacks on the heart of Iran’s nuclear and military structure Friday, deploying warplanes and drones previously smuggled into the country to assault key facilities and kill top generals and scientists — a barrage it said was necessary before its adversary got any closer to building an atomic weapon.