T lymphocytes are components of the immune system that are located in the tumor environment. They serve to identify and remove tumor cells. In order to perform this function, they must produce a large ...

Lymphocytes rely on precisely regulated protein dynamics to execute immune surveillance, activation and effector functions. Central to this regulation are post-translational modifications, ...

• CPEB4 allows these immune cells to adapt to the chronic stress caused by the massive secretion of cytokines, which are essential for them to adopt their effector function and kill cancer cells. • ...

Pharmacokinetic analysis of two dose levels of rasburicase in adult patients with hematologic malignancies at high or potential risk for tumor lysis syndrome No significant financial relationships to ...

CD4+ T cells, or helper T cells, are one type of lymphocyte that helps coordinate the immune response against infection and disease. They interact and activate other cells in the immune system. The ...

In a recent study published in Nature, researchers developed a blood nutrient molecule library and conducted screenings to find dietary components that impact anti-tumor immunity. Dietary nutrients ...

Targeted next-generation DNA sequencing of paired tumor and normal DNA to reveal frequent actionable germline alterations.