By fusing enzyme fragments to antibodies, researchers from the Institute of Science Tokyo, in Japan, developed an innovative enzyme switch called "Switchbody," which is activated when bound to its ...

At 10 one-millionths of a meter wide, a single human cell is tiny. But something even smaller exerts an enormous influence on ...

Phenylalanine hydroxylase (PheOH) catalyzes the conversion of phenylalanine to tyrosine, a rate-limiting step in phenylalanine catabolism and protein and neurotransmitter biosynthesis (for recent ...

Scientists have uncovered a surprising connection between sugar metabolism and alcohol addiction, identifying a potential new ...

Mechanistically, the chemists think that in the presence of the enzyme, there’s a formal hydrogen atom abstraction that is ...

Immunometabolism have advanced the understanding of dynamic interplay between metabolic pathways and immune responses.

Researchers have discovered that the enzyme NUDT5 utilizes its structure to exercise metabolic control over a key pathway in ...

Sage Therapeutics Inc. has described sterol derivatives acting as glutamate receptor ionotropic, NMDA 2A (GRIN2A; GluN2A) negative allosteric modulators reported to be useful for the treatment of ...