Sampson (calf/hand) is not in line to practice Wednesday, Daniel Oyefusi of ESPN.com reports.

Cleveland Browns quarterback Shedeur Sanders completes a 31-yard pass to running back Dylan Sampson during Week 14 of the 2025 NFL season.

Preview the player prop betting lines, stats and more for Dylan Sampson before his Cleveland Browns play the Tennessee Titans in a Week 14 NFL

Sampson will miss his first game of the season while managing a pair of injuries. His next chance to take the field will come Week 16 against the Bills. As long as Sampson is sidelined, Cleveland's main depth options behind Quinshon Judkins will be Raheim Sanders and Trayveon Williams.

Browns rookie Dylan Sampson had dealt with a mostly-quiet first season until he hit on a pair of big plays in the Week 12 win over the Raiders.

The Cleveland Browns are now led by rookie quarterback Shedeur Sanders. Sanders was sitting deep in the Browns' quarterback room to start the season, behind Joe Flacco, Kenny Pickett and Dillon Gabriel.

The Cleveland Browns missed out on a chance to win their fourth game due to miscommunication between Quinshon Judkins and Gage Larvadain. But running back Dylan Sampson opened up about what happened on the play where Judkins held on to the ball,

Fantasy football playoffs are here, which means every lineup decision suddenly feels like it carries the emotional weight of a midseason coaching change. One wrong call and you’re doom-scrolling your league chat;

Determining who makes a better last-minute waiver pickup between Cleveland Browns running back Dylan Sampson and New Orleans Saints back Devin Neal.

Cleveland Browns rookie running back Dylan Sampson made his feelings clear on Shedeur Sanders remaining the quarterback.

With Shedeur Sanders and Cam Ward coming up against one another, the game between the Cleveland Browns and the Tennessee Titans was expected to be some sort of rivalry game.