That is, until now. Eddy Pineiro has been revolutionary for the 49ers and has been key to the 49ers' success this season.

The 49ers need plenty more of that in the final stretch as not only do they face better defenses but much better offenses.

NFL Week 16 odds, picks, predictions, TV channel, streaming information for Monday Night Football between San Francisco 49ers ...

The Tennessee Titans placed three safeties on injured reserve after their Week 15 loss to the 49ers, forcing emergency roster ...

An ESPN analyst believes the 49ers can make noise in the playoffs, but one fatal flaw could derail San Francisco's postseason ...

Christian McCaffrey is expected to play vs. the Titans on Sunday, a source said, despite being added to the injury report as ...

The 49ers' offense is about the same as 2024. The defense is worse. The special teams, though, has taken a historic leap. Is ...

The San Francisco 49ers have signed wide receiver Javon Baker to the practice squad, adding depth to their receiving corps.

Despite losing to the Seattle Seahawks on Sunday in his first start since the 2020 season, Indianapolis Colts veteran ...

The 49ers put Tennessee away, then let the Titans back in for a 37-24 win that featured efficient offense and concerning ...

The San Francisco 49ers added running back Christian McCaffrey gave fans quite a scare on Saturday by adding him to the ...

But before some optimism could be built, the 49ers got a concerning injury update on Christian McCaffrey's back. However, ...