Although 49ers receiver Ricky Pearsall reinjured the knee that kept him out of six games earlier this season, coach Kyle ...

San Francisco 49ers defensive lineman Keion White is taking Monday's matchup against Indianapolis Colts quarterback Philip ...

There's nothing like a good hot streak in December when it comes to picking NFL games. For me, it's been a bit of a heater. I went 11-5 both straight up and against the spread las ...

Professional sports bettors and handicappers make predictions on NFL Week 16 games and College Football Playoff first-round ...

Colts quarterback Philip Rivers should face less pressure his second week back in the NFL, as his team plays the 49ers on ...

The Chiefs (6-8) need to win out starting with Sunday’s visit to Tennessee to continue the streak of a winning record in each of coach Andy Reid’s 13 seasons.

2. New England Patriots (11-3), AFC East leaders: Their 10-game heater snapped, they failed to clinch the division Sunday and ...

The SportsLine Projection Model has revealed its Los Angeles Rams vs. Seattle Seahawks picks for 'Thursday Night Football' in ...

With three games left to play, the Indianapolis Colts must unleash a quarterback duo that can fully unlock the offense.

We list three ways LA can earn a win with the NFC"s top seed likely at stake, as well as three ways Seattle can prevent it ...

In a battle for first place in the NFC West and the No. 1 seed, the LA Rams visit the Seattle Seahawks Thursday night.

The 49ers aren't taking Philip Rivers lightly as the veteran QB returns with the Colts, setting up a high-stakes Monday night ...