Iran conflict could open opportunities for Russia to possibly become a power broker to help end the confrontation.

The U.S. military is operating in the air, on land and at sea to shoot down Iranian missiles fired at Israel.

At least ten people were killed in Israel overnight, after multiple Iranian missiles evaded the country's advanced defense systems. Explosions rocked Tehran, but casualties weren't immediately clear.

The Israeli military has warned that “all of Israel is under fire” after Iran launched retaliatory strikes on Friday, following Israel’s attacks on Iranian military and nuclear targets.

The U.S. says it wasn't involved in the strikes on Iran, but three American officials told NBC News the U.S. is assisting in shooting down Iranian missiles and projectiles targeting Israel.

The retaliatory strikes came on Saturday, a day after Israel killed top Iranian military leaders and scientists and destroyed an aboveground nuclear enrichment plant near Natanz.

Iranian strikes carried out overnight against Israel took at least 10 lives, according to Israel’s Magen David Adom rescue service.

Israel’s ongoing attacks on Iranian nuclear sites killed 78 people and wounded more that 320 on Friday, said Iran’s ambassador to the United Nations. The strikes killed generals and scientists, but the ambassador told the U.N. Security Council that “the overwhelming majority” of victims were civilians.

US intelligence has reported that Iran has 2,000 ballistic missiles, many of which are capable of carrying 900 kg warheads. Iran's goal is for the number of its missiles to exceed the number of Israeli air defense interceptors.