Structured illumination microscopy (SIM) is the most preferable system for live-cell super-resolution imaging. It enables the observation of intricate subcellular dynamics. However, conventional SIM ...

Three-dimensional (3D) imaging is essential for investigating cellular structure and dynamics. Traditional optical methods rely on adhesive or mechanical forces to hold and scan cells, which limit ...

Figure | Working principle of Interferometric Image Scanning Microscopy (iISM). (a) Schematic of the iISM microscope and interferometric PSF detection. (b) iISM with adaptive pixel-reassignment (APR) ...

Cells are like metropolises, home to millions of molecular residents. If one were to stand atop a high-rise, trying to ...

System could enable study of complex biological processes in live animals over long periods with less tissue damage than ...

A robust, image-based neurotoxicity assay helps scientists streamline subcellular neuronal analysis with live-cell dyes and high-throughput automated microscopy. Neuronal cell culture models allow ...

A hybrid microscope allows scientists to simultaneously image the full 3D orientation and position of an ensemble of molecules, such as labeled proteins inside cells. The microscope combines polarized ...

Deep inside a small, windowless room at the University of California, Berkeley, two microscopes are quietly capturing some of the most detailed views of life ever recorded. Day and night, they collect ...

Microscopy generates more image data than any single research group can interpret manually, and AI microscopy and biological imaging tools have become the practical answer to that scale problem. Deep ...

Peking University, Aug 18, 2025: Professor Xi Peng’s team from the College of Future Technology at Peking University has recently developed a triangle structured illumination microscopy (SIM), which ...