NRG Therapeutics has dosed the first participants in its Phase I clinical trial of NRG5051, being developed as a ...

An HIV-derived nucleoside therapy now treats rare genetic diseases by restoring mitochondrial DNA and improving muscle ...

Tisento Therapeutics today announced that the global Phase 2b PRIZM study is fully enrolled. PRIZM is evaluating zagociguat – a once-daily, oral investigational medicine – as a treatment for the rare ...

NRG5051 is a first-in-class, orally bioavailable and CNS-penetrant next-generation inhibitor of the mitochondrial permeability transition pore (mPTP), acting through a novel undisclosed ...

A new study reveals that nerve cells receive periodic infusions of mitochondria from neighboring cells — and this may point ...

This perspective argues that Parkinson’s disease may involve functional iron deficiency, where bioavailable iron is limited despite normal or elevated total iron in the brain. The authors propose that ...

The AHA recommended whole exome or whole genome sequencing as first-line diagnostic tools for mitochondrial diseases.

Many people with multiple sclerosis struggle with balance and coordination, and this study uncovers a hidden reason why.

In a new study published in Liver Research, a team of researchers in China discovered that nicotinic acid-a common form of ...

Diabetes doesn’t just coexist with heart disease - it actively reshapes the heart’s machinery and the way it makes energy.

The study reveals that nicotinic acid (vitamin B3) significantly protects the liver during ischemia-reperfusion injury by ...

Amanda LaValle was shocked to learn her daughter Iris is one of only six people on record to have been diagnosed with a rare disease Amanda LaValle When Amanda LaValle's daughter Iris Hope was ...